NKX2-6 mutation predisposes to familial atrial fibrillation
نویسندگان
چکیده
منابع مشابه
NKX2-6 mutation predisposes to familial atrial fibrillation.
Atrial fibrillation (AF) is the most common form of sustained cardiac arrhythmia and is associated with substantially increased morbidity and mortality rates. Aggregating evidence demonstrates that genetic defects are involved in the pathogenesis of AF and a number of AF-associated genes have been identified. Nevertheless, AF is a genetically heterogeneous disorder and the genetic components un...
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Dilated cardiomyopathy (DCM) is the most prevalent type of primary myocardial disease, which is the third most common cause of heart failure and the most frequent reason for heart transplantation. Aggregating evidence demonstrates that genetic risk factors are involved in the pathogenesis of idiopathic DCM. Nevertheless, DCM is of remarkable genetic heterogeneity and the genetic defects underpi...
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Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia associated with substantial morbidity and mortality. Genetic variants play important roles in the pathogenesis of AF. However, AF is a genetically heterogeneous disorder, and the genetic determinants in most patients with AF remain to be identified. In this study, the entire coding region of the connexin40 gene, encoding t...
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A trial fibrillation (AF) is a common arrhythmia associated with substantial morbidity and a markedly increased risk of ischemic stroke. It accounts for one third of all strokes in patients above the age of 65 and is also associated with an increased mortality. In recent years, risk models for AF prediction have been developed based on clinical and demographic variables. AF may also present as ...
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ژورنال
عنوان ژورنال: International Journal of Molecular Medicine
سال: 2014
ISSN: 1107-3756,1791-244X
DOI: 10.3892/ijmm.2014.1971